ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
FDA analysis of 40-years of antibacterial development: Dheman et al.
FDA: Early endpoints and late endpoints suggest a path to global regulatory convergence (Bart et al.)
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
Global survey of novel antibiotic reimbursement models / PASTEUR Act introduced to US House
Draft FDA guidance on anti-infectives for children: It’s (mostly) all about PK and safety
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
NIAID workshop: What is a robust PK-PD package?
Developing antibiotics for children: There are no easy answers
The 6 meanings of “Lack of Access” (UNSLAP)
Modeling the value of an effective antibiotic — Megiddo et al.
FDA workshop: Insights on inhaled antifungals and antibacterials
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet